Section 1: Basic Science and Spinal Assessment
1. Basic Science of Degenerative Disk Disease 3
Anthony Petrizzo, Kristina Bianco
• Morphology of the Normal IVD 3
• Morphologic Changes in the Degenerative IVD 4
• Etiology of IVD Degeneration 5
• Inflammatory Mediators 7
• Novel Management Techniques 8
2. Biomechanics of the Spine 11
Antonio Valdevit
• The Spinal Column 11
• Intervertebral Disk 12
• The Facet Joint and Uncovertebral Joint 12
• Spinal Motion 13
• Spinal Loading 13
• Spinal Arthroplasty 15
• Mechanical Evaluation and Clinical Implications of Spinal Instrumentation 16
3. Balance, Posture and Stability in Spinal Disorders 18
Virginie Lafage, Barthelemy Liabaud, Frank Schwab, Jean-Pierre Farcy
• Balance, Stability and Posture 18
4. Differential Diagnosis of Spinal Disorders 23
Michael Gerling, Vadim Goz
• Risk Factors 23
• Prognosis 23
• Types of Pain 24
• Chronic Pain Syndromes and Threshold Modulation 24
• Differential Diagnosis 24
5. Neurological Differential Diagnosis of Spinal Disorders 30
Devon Ryan, Thomas Cheriyan, Ludmilla Bronfin
• Conditions that Mimic Radiculopathy 30
• Conditions that Mimic Cervical Myelopathy 33
6. Examination and Evaluation of Neck Pain 36
Jonathan R Stieber, Robert J Ames
• Prevalence and Natural History 36
• Anatomy 36
• Pathophysiology 37
• History, Physical Examination and Grading 39
• Imaging and Diagnostic Studies 41
7. Examination and Evaluation of Low Back Pain 44
Devon Ryan, Jeffery Perry
• Institutional Guidelines 44
• Examination and Evaluation of Acute Low Back Pain 45
• Examination and Evaluation of Chronic Low Back Pain 48
xiv Spinal Disorders and Treatments: The NYU-HJD Comprehensive Textbook
8. Clinical Examination and Evaluation of Radiculopathy: A Neurological Perspective 49
Kiril Kiprovski
• History and Physical Examination 49
• Somatic Referred Pain from the Neck and Lower Back 54
• Red Flags 57
9. Evaluation of Adolescent Scoliosis 60
Stephen P Maier II, Thomas Cheriyan, Baron S Lonner
• Evaluation of Scoliosis 62
• Classification 67
10. Evaluation of Adult Spinal Deformity 69
Jeffrey H Weinreb, Pierre Devos, Frank Schwab
• Evaluation 69
• Spine Related Measurements in the Setting of Adult Spinal Deformity 71
• Classification 71
11. Measurement of Adult Spinal Deformity 75
Jeffrey H Weinreb, Thomas Cheriyan, Virginie Lafage, Frank Schwab
• Imaging 75
• Coronal Plane Measurements 75
• Sagittal Plane Measurements 77
• Spinopelvic Radiographic Parameters 77
• Global Alignment 78
• Criticism of 2D Measurements 78
• 3D Analysis 78
12. Assessment of Disability 81
Juan Carlos Robles
• Functional Assessment Instruments 81
• Objective Tools 81
• Subjective Tools 83
13. Non-MRI Evaluation of the Cervical and Lumbar Spine 85
Tony Wong, Gina Ciavarra, Leon Rybak
• Radiographs 85
• Computed Tomography 88
• Nuclear Medicine 95
• Ultrasound 100
14. MRI Evaluation of Cervical and Lumbar Spine Disorders 102
Michael B Mechlin
• Cervical Spine 102
• Lumbar Spine 108
15. Interventional Diagnostic Procedures: Nerve Blocks and Discography 120
Steven Calvino, Jessie Ng
• Diagnostic Nerve Blocks 120
• Discography 121
• Anatomy and Function of the Intervertebral Disk 121
• Disk Degeneration and Pain 123
• Procedure 123
• Complications 123
• Evidence 124
Contents xv
16. Rheumatic Diseases and Myofascial Pain 126
Brian D Golden
• How to tell the Difference between ‘‘-ITIS’’ and ‘‘-ALGIA’’ 126
• Ankylosing Spondylitis as the Prototypical Inflammatory, Rheumatologic Disease Affecting the Spine 126
• Fibromyalgia as the Prototypical Noninflammatory Pain Syndrome 128
17. Diagnosis of Osteopenia and Osteoporosis 130
Stephen Honig, Stephen P Maier II
• Pathogenesis of Postmenopausal Osteoporosis 132
• Diagnosing Osteopenia and Osteoporosis 132
Section 2: Non-Invasive Therapeutic Intervention
18. Multidisciplinary Approach to Spinal Pain 139
Kseniya Slobodyanyuk, Thomas Cheriyan, Christopher Gharibo
• Spinal Pain Pathophysiology 139
• Pharmacologic Treatment 139
• Nonpharmacologic Treatment 141
• Functional Rehabilitation 141
19. Pharmacological Management of Spinal Pain: Narcotics 144
Christopher Gharibo
20. Pharmacological Management of Spinal Pain: Non-narcotics 147
Juan Carlos Robles, Thomas Cheriyan
• Acetaminophen 147
• Nonsteroidal Anti-Inflammatory Drugs 147
• Steroids 147
• Anticonvulsants 148
• Tricyclic Antidepressants 149
• Muscle Relaxants 149
• Nonopioid Combination Medication 149
• Topical Medications 150
21. Prevention and Management of Addiction 151
Marianne T Guschwan
• The Scope of the Problem with Opioids 151
• Addiction Management 152
• Prevention of Addiction 152
22. Therapeutic Management of Osteoporosis 155
Stephen Honig
• Aging, Falling, and the Concept of Frailty 155
• Calcium and Vitamin D Supplementation 156
• Bone Strengthening Prescription Medications 156
23. Nonoperative Treatment of Cervical Myelopathy and Radiculopathy 159
Kristina Bianco, Faruk Razzak, Gerard Varlotta
• Task Force for Neck Pain 159
• Pathophysiology 160
• Nonoperative Treatment for Cervical Myelopathy and Cervical Radiculopathy 161
• Other Nonoperative Treatment Methods 164
xvi Spinal Disorders and Treatments: The NYU-HJD Comprehensive Textbook
• Nonoperative versus Operative Treatment of Cervical Myelopathy 164
• Nonoperative versus Operative Treatment of Cervical Radiculopathy 165
24. Alternative Medicine Treatment in Spinal Disorders: Application of Acupuncture 168
Alex Moroz, Brian Freed
• Applications of Acupuncture 169
25. Psychosocial Aspects and Management of Chronic Low Back Pain 171
Matthew B Smith
• Aversion 171
• Central Sensitization 172
• Psychiatric Comorbidity 172
• Personality Factors 173
• Interpersonal and Social Factors 173
• Chronic Illness 174
• Psychiatric and Psychological Treatment Considerations 174
• Countertransference 175
26. A Conservative Care Approach to the Rehabilitation of Patients with Spine Pain 178
Angela Lis, Sherri Weiser
• Triage Criterion 1: Duration of SP 180
• Triage Criterion 2: The Presence of Yellow Flags 180
• Triage Criterion 3: Is the Patient a Candidate for an Intensive Interdisciplinary Conditioning Program? 182
Section 3: Spinal Injection
27. Introduction to Spinal Injections 187
Jamie R Terran, Rachel N Rattenni, Faruk Razzak, Gerard P Varlotta
• History 187
• Trigger Point Injections 187
• Sacroiliac Injections 188
• Peripheral Joint Injections 189
• Sympathetic Nerve Blocks 189
• Epidural Injections 189
• Intra-articular Facet Injections 190
• Median Branch Blocks and Rhizotomy 190
• Intradiscal Electrothermal Therapy, Nucleoplasty, and Biacuplasty 190
• Spinal Cord Stimulators 191
• Complications and Risks 191
28. Diagnostic and Therapeutic Value of Spinal Injections 193
Juan Carlos Robles, Vadim Goz
• Discograms 193
• Epidural Steroid Injections 194
• Selective Nerve Root Blocks, Facet Joint Blocks, and Medial Branch Blocks 195
29. Trigger Point Injections 200
Benjamin Bieber, Devon Ryan
• Diagnosis 200
• Indications 201
• Technique 202
Contents xvii
• Preinjection Block 203
• Evidence 203
30. Sacroiliac Injections 205
Jackson Liu, Jeffrey Weinreb, Wayne Stokes
• Anatomy 205
• Diagnosis 205
• Injection 208
• Injection Technique 209
• Complications 210
• Newer Techniques 210
31. Peripheral Joint and Soft Tissue Injections 212
Warren Young
• Injectables 212
• Injection Techniques 216
32. Sympathetic Blocks: Utility in Complex Regional Pain Syndrome 221
Kseniya Slobodyanyuk, Christopher Gharibo
• Nociceptive and Neuropathic Pain 221
• Complex Regional Pain Syndrome 221
• CRPS Management 223
33. Epidural Steroid Injections 228
Kseniya Slobodyanyuk, Christopher Gharibo
• Epidural Steroid Injections 228
• Interlaminar, Transforaminal, and Caudal ESIs 229
• Complications 231
34. Intra-articular Facet Injections 233
Kristina L Bianco, Jeffrey H Weinreb, Gerard P Varlotta
• Facet Joint Anatomy 233
• Etiology and Pathophysiology 233
• Grading Scales for Facet Joint Arthropathy 235
• Diagnosis 235
• Imaging 236
• Treatment 236
• Indications for Injections 237
• Intra-Articular Facet Joint Injections 237
• CYST Intervention Results 238
• Complications 238
• Differential Diagnosis 238
35. Complications of Spinal Injections 240
Brian Forzani, Stephen P Maier II, Kseniya Slobodyanyuk, Thomas J Errico, Thomas Cheriyan, Christopher Gharibo
• Regional/Mechanical Injury 240
• Needle/Injectate-Related Injuries 241
• Pressure-Related Injuries 243
• Infections 244
• Vascular Injury 244
• Neural Complications 248
• Chemical Injury 249
xviii Spinal Disorders and Treatments: The NYU-HJD Comprehensive Textbook
36. Medial Branch Block and Rhizotomy 253
Devon Ryan, Jamie Terran, Mohammed Khan
• Medial Branch Block 254
• Rhizotomy (Medial Branch Neurotomy, Radiofrequency Neurotomy) 256
37. Intradiscal Electrothermal Therapy, Nucleoplasty and Biacuplasty 259
Steven Calvino, Rohan Bannis, Sachin Shah
• Intradiscal Electrothermal Therapy 260
• Nucleoplasty 260
• Biacuplasty 261
38. Spinal Cord Stimulators 264
Brian Park, Yong H Kim
• What are Spinal Cord Stimulators? 264
• Indications 265
• Ischemic/Visceral Pain 265
• Neurogenic Pain 265
• Spine-Related Conditions 265
• Technique 266
• Trial/Screening 266
• Permanent Implantation 267
• Complications 268
Section 4: Surgical Management
39. History of Surgical Management of Spinal Disorders 273
Justin Paul, Thomas Cheriyan, Thomas J Errico
• Decompression of Spinal Elements 274
• Stabilization of the Spine 276
• Antibiotics and Orthopedic Instrumentation 277
• Posterior Thoracolumbar Instrumentation 278
• Anterior Thoracolumbar Instrumentation 278
• Posterior Cervical Instrumentation 280
• Anterior Cervical Instrumentation 280
• Interbody Fusion 280
• Alternatives to Fusion—Total Disk Replacement 282
• Deformity Correction 282
• Rods for Distraction and Compression 282
• Segmental Fixation for Increased Rigidity 283
• Multiple Hook Rod for Rotation 283
40. Surgical Management of Lumbar Degenerative Spondylolisthesis 286
Qasim M Husain, Robert P Norton, Jeffrey M Spivak
• Pathogenesis 286
• Incidence 286
• Presentation 287
• Nonoperative Measures 287
• Surgical Options 287
• Case Example 292
Contents xix
41. Differentiating Cervical Radiculopathy and Peripheral Compressive Neuropathy 294
Themistocles S Protopsaltis, John A Bendo
• Epidemiology 294
• Clinical Presentation and Relevant Anatomy 294
• C8 Radiculopathy vs Cubital Tunnel Syndrome vs T1 Radiculopathy 296
• Physical Examination 297
• Electrodiagnostic Studies 299
• Peripheral Entrapment Neuropathies and NCS 299
• Treatment 299
• Surgical Results 300
42. Surgical Management of Cervical Disk Herniation 301
Kseniya Slobodyanyuk, Jonathan Stieber
• Epidemiology 301
• Signs and Symptoms 301
• Treatment 302
• Surgical Options 302
• Anterior Approach 302
• Posterior Approach 303
• Selection of Approach 304
• Complications 306
43. Surgical Treatment of Cervical Stenosis 310
Jane S Hoashi, Stephen P Maier II, Jeffrey D Klein
• Cervical Spondylotic Radiculopathy 310
• Cervical Spondylotic Myelopathy 311
• Pathogenesis 311
• Treatment Options 313
• Anterior Approach 314
• Posterior Approach 317
• Laminoplasty 318
• Posterior Laminoforaminotomy 320
44. Operative Management of Degenerative Cervical Disorders 324
Hiroyuki Yoshihara, John A Bendo
• Surgical Indications 324
• Surgical Options 325
• Surgical Outcomes 328
• Complications 329
45. Newer Motion Preservation Technologies 332
Kseniya Slobodyanyuk, Rachel N Rattenni, Thomas Cheriyan, Thomas J Errico
• Nucleus Replacement 332
• Synthetic Nucleus Replacement 332
• Interspinous Distraction 334
• Dynamic Stabilization 334
• Facet Replacement 335
• Annulus Repair 336
46. Minimally Invasive Lumbar Spine Fusion 337
Noel I Perin
• Indications 337
• Anterior Approaches (ALIF) 337
xx Spinal Disorders and Treatments: The NYU-HJD Comprehensive Textbook
• Posterior Approaches 340
• Discussion 343
47. Cervical Total Disk Replacement 345
Robert P Norton, Jeffrey A Goldstein
• Evolution of Implants 345
• Technical Considerations 346
• Indications and Contraindications 347
• Analysis of the FDA IDE Trials 347
• Further Literature Analysis 347
• Complications 349
• Case Example 350
48. Lumbar Total Disk Replacement Surgery 354
Hiroyuki Yoshihara, John A Bendo
• Indications for Lumbar Total Disk Replacement 354
• Surgical Approach and Technique 355
• Prostheses 355
• SB Charité III 355
• Complications 358
49. Conventional, Microscopic and Endoscopic Surgical Treatment of Lumbar Disk Herniations 361
Bartosz Grobelny, Michael L Smith
• History 361
• Modern Techniques 361
• Comparative Trials 365
50. Surgical Treatment of Lumbar Spinal Stenosis 369
Stephen P Maier II, Jane S Hoashi, Jeffrey D Klein
• Clinical Features 369
• Physical Examination and Differential Diagnosis 370
• Diagnostic Imaging 370
• Electrodiagnostic Studies 371
• Indications for Surgery 371
• Surgical Treatment 371
• Surgical Outcomes 373
• Interspinous Spacer Technology 374
51. Overview of Spinal Deformity Surgery 378
Justin Paul, Thomas Cheriyan, Anthony Petrizzo, Thomas J Errico
• Anatomy and Biomechanics 379
• Clinical Evaluation 381
• Radiologic Evaluation 381
• Classification 382
• Treatment 383
52. Operative Management of Pediatric Deformities 388
Justin C Paul, Baron S Lonner, Courtney S Toombs
• Scoliosis 388
• Anatomy/Biomechanics 388
• Clinical Evaluation 389
• Radiologic Evaluation 392
• Classification 393
• Nonoperative Treatment 394
Contents xxi
• Operative Treatment 395
• Surgical Technique 395
• Outcomes/Complications 397
• Kyphosis 399
• Spondylolisthesis 400
53. Surgical Treatment of Adult Degenerative Deformity 406
Jeffrey B Knox, Justin Paul, Frank Schwab
• Surgical Indications 406
• Presurgical Considerations 407
• Surgical Planning 407
• Surgical Techniques 407
• Staged Operations 410
• Complications 410
54. Surgical Interventions in Osteoporosis and Compression Fracture 414
Peter G Passias, Andy Chang
• Osteoporotic Compression Fractures 414
• Conservative Management 414
• Surgical Treatment 415
• Adverse Events for Vertebroplasty and Kyphoplasty 417
55. Surgical Management of the Rheumatoid Spine 420
Ronald Moskovich, Jeffrey Knox
• Spine Manifestations 420
• Clinical Evaluation 421
• Natural History 421
• Grading 421
• Imaging 421
• Treatment 423
• Surgical Options 425
56. Traumatic Cervical Spinal Fracture Surgery 429
Justin C Paul, Robert Norton, Themistocles Protopsaltis
• Cervical Spine 429
• Classification 434
• Nonoperative Treatment 437
• Operative Treatment 438
• Classification 444
• Operative Care to Optimize Function 445
57. Thoracolumbar and Sacral Fracture Surgery 448
Robert Norton, Justin C Paul, Themistocles Protopsaltis
• Anatomy and Mechanism of Injury 448
• Clinical Evaluation 448
• Radiologic Evaluation 448
• Classification 449
• Compression Fractures 449
• Burst Fractures 450
• Flexion-Distraction Injuries 451
• Fracture-Dislocation Injuries 451
• Low Lumbar Injuries 452
• Treatment Goals 452
xxii Spinal Disorders and Treatments: The NYU-HJD Comprehensive Textbook
58. Tumors of the Spine 456
Donato Pacione, Irene Kim, Dimitris Placantonakis, Anthony Frempong-Boadu
• Primary Extradural Spinal Tumors 456
• Intradural Extramedullary Spinal Tumors 461
• Intradural Intramedullary Spinal Tumors 463
• Spinal Metastases 468
59. Intraoperative Monitoring in Spine Surgery 482
Thomas Cheriyan, Rachel N Rattenni, Jerry Cheriyan, Athena M Lolis, Thomas J Errico
• Stagnara Wake-Up Test 482
• Somatosensory Evoked Potential 482
• Motor Evoked Potentials 483
• Spontaneous EMG 484
• Triggered EMG 485
• Multimodal Intraoperative Monitoring 486
Index 489
Trastornos y tratamientos de la columna vertebral
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Este libro de texto proporciona a sus lectores una comprensión básica de los principios que subyacen en el vasto campo de los trastornos de la columna. Lo hace destacando los aspectos fundamentales de la anatomía, la biomecánica, el diagnóstico y el manejo de los trastornos de la columna. El libro de texto está organizado en cuatro secciones que corresponden a las cuatro etapas del continuo del cuidado de la columna: ciencia básica y evaluación de la columna, intervención terapéutica no invasiva, inyección de la columna y manejo quirúrgico. Cada sección se centra en aplicaciones de modalidades terapéuticas basadas en la evidencia y centradas en el paciente. Se ha puesto especial énfasis en el manejo tanto quirúrgico como no quirúrgico de las afecciones de la columna. Este libro de texto está destinado a ayudar tanto a los profesionales médicos como a los pacientes a mejorar su comprensión y conocimiento de las afecciones de la columna.
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